B2B integration doesn’t usually grab headlines, but it’s the invisible backbone that keeps companies working together without chaos. When your supply chain, ERP, CRM, and other tools need to talk to your partners’ systems without missing a beat, that’s where B2B integration specialists come in. These companies handle the gritty work of connecting data flows, mapping processes, and automating exchanges so people don’t have to manually push files around.

In this article, we’re taking a closer look at companies that build B2B integrations that hold up in the real world – where formats vary, logic breaks, and timelines matter.

 

1. OSKI Solutions

At OSKI Solutions, we build software that holds up over time. Our work isn’t just about ticking boxes or wiring systems together. We take a structured approach to how data moves, how applications talk to each other, and how everything fits into the bigger picture. Whether it's integrating APIs, connecting cloud platforms, or supporting B2B communication across systems, we focus on reliability and clarity. Most of our projects come down to solving real-world challenges where clean architecture matters.

We're comfortable working across different technologies and industries, from logistics and retail to education and energy. We’ve shaped solutions that aren’t just functional, but maintainable and scalable too. Our team works closely with clients to understand how systems are being used and what they’re supposed to achieve. It’s not about shiny features or trends. It’s about getting the integration right so teams can stop worrying about tech and focus on actual work.

Key Highlights:

• Strong foundation in structured system integration
• Focus on long-term maintainability, not one-off fixes
• Experience with both cloud-native and hybrid architectures
• Team includes seasoned architects, project leads, and QA
• Clear communication and stable delivery practices

Services:

• B2B system integration
• API architecture and implementation
• Cloud infrastructure and deployment (AWS, Azure, GCP)
• Frontend and UI/UX development (React, Vue, Angular, etc.)
• AI-driven integrations and automation workflows
• CRM and finance software integration
• Progressive web app development
• Ongoing support and software maintenance

Contact Information:

• Website: oski.site 
• E-mail: contact@oski.site
• LinkedIn: www.linkedin.com/company/oski-solutions
• Address: Estonia, Tallinn, Kaupmehe tn 7-120, 10114
• Phone: +48571282759

 

 

 

 

2. Avantor

Avantor approaches B2B integration from a practical, operations-first perspective. Their focus is on making procurement workflows easier to manage and less prone to error. By connecting systems through standard protocols and streamlining how businesses interact with suppliers, they help teams reduce manual reconciliation and control maverick spending. Their integration setup supports everything from punch-out catalogs to hosted pricing, with options tailored to how each organization prefers to operate. 

Their team brings both technical and process knowledge to each engagement. They work with a wide range of ERP systems and procurement platforms, using structured project management and industry protocols like EDI and XML to avoid bottlenecks. Each project includes a dedicated manager and access to help desk support, which helps speed up adoption and reduce friction. From real-time inventory syncing to simple invoice handling, they focus on the core goal: smoother day-to-day transactions that don’t require a second thought.

Key Highlights:

• Integrations tailored to procurement teams and vendor workflows
• Hands-on project management and support
• Standard EDI/XML-based transaction handling
• Supports multiple catalog and punch-out formats
• Embedded training and documentation

Services:

• B2B integration for procurement and ERP systems
• Hosted and punch-out catalog implementation
• EDI/XML order, invoice, and shipping integration
• Technical consulting and project coordination
• User training and ongoing help desk support

Contact Information:

• Website: www.avantorsciences.com
• E-mail: CS.Specialist@avantorinc.com
• Facebook: www.facebook.com/Avantorinc
• Twitter: x.com/Avantor_News
• LinkedIn: www.linkedin.com/company/avantorinc
• Address: One Radnor Corporate Center, Building One, Suite 200, 100 Matsonford Road, Radnor, PA 19087
• Phone: +1 855 282 6867

 

3. Aspire Systems

Aspire Systems takes a structured, protocol-driven approach to B2B and EDI integration. Their work is centered on enabling consistent, secure data exchange between trading partners using formats like X12, EDIFACT, HL7, and others. Whether building new integrations or modernizing outdated setups, they help organizations streamline how electronic documents are handled and reduce manual overhead. Much of their effort goes into making these systems more agile and scalable, which in turn makes it easier for businesses to onboard partners and adapt as needs shift.

Their offering includes both consulting and implementation, with services covering partner onboarding, trading document workflows, and managed support. Aspire’s experience in consolidating communication gateways and enforcing real-time validation helps reduce order errors and improves visibility across the network. They also support various transfer options like AS2 and secure FTP, helping clients stay aligned with compliance and performance requirements. 

Key Highlights:

• Deep knowledge of EDI formats and B2B standards
• Support for both legacy and modern integration environments
• Structured onboarding and partner management processes
• Real-time validation and automated compliance
• Long-term support via managed services

Services:

• B2B/EDI integration consulting and architecture design
• Trading partner setup and management
• Multi-protocol communication (AS2, FTP, Web Services)
• EDI mapping and data transformation
• Managed B2B integration support

Contact Information:

• Website: www.aspiresys.com
• E-mail: info-india@aspiresys.com
• Facebook: www.facebook.com/AspireSystems
• Twitter: x.com/aspiresystems
• LinkedIn: www.linkedin.com/company/aspire-systems
• Instagram: www.instagram.com/aspire_systems
• Address: 1/D-1, SIPCOT IT PARK, Siruseri, Chennai - 603 103, Tamil Nadu, India
• Phone: + 91 44 6740 4000

 

4. Tellestia

Tellestia focuses on reducing friction in B2B communication by automating how data moves between systems and partners. Their EDI and B2B integration services are built to help companies shift from manual workflows to more automated, scalable processes. Their setups are flexible enough to support multiple trading partner connections, and they place strong emphasis on compliance, accuracy, and operational reliability. Whether it's mapping data, managing partner connections, or upgrading legacy setups, their services are built to remove complexity without overengineering the solution.

They handle a wide mix of integration challenges across industries like manufacturing, retail, and telecom. Their team is experienced in translating data into standardized formats, maintaining compliance with frameworks like GDPR and HIPAA, and monitoring integrations to avoid disruptions. A key focus is giving teams real-time visibility and reducing error rates, which helps improve collaboration with suppliers and partners over the long term. For companies struggling with disconnected systems or paper-based processes, Tellestia offers a direct way forward.

Key Highlights:

• B2B integration architecture with support for legacy systems
• Compliance-ready solutions (GDPR, HIPAA, etc.)
• Real-time monitoring and error handling
• Expertise in EDIFACT, ANSI X12, HL7, and more
• Focus on reducing manual tasks and improving data accuracy

Services:

• B2B EDI integration implementation
• Data mapping and transformation services
• Managed integration support and monitoring
• Partner onboarding and legacy modernization
• Consulting for system upgrades and integration design

Contact Information:

• Website: tellestia.com
• E-mail:  info@tellestia.com
• Facebook: www.facebook.com/tellestia
• Twitter: x.com/tellestia
• LinkedIn: www.linkedin.com/company/tellestia
• Address: Tecci Park, No 285, Rajiv Gandhi Salai, Kumaran Nagar, Elcot SEZ, Karapakkam, Chennai, Tamil Nadu - 600119
• Phone: +91-9840369635

 

5. Coneksion

Coneksion takes a cloud-first, low-friction approach to B2B integration using an iPaaS model. Their focus is on simplifying complex supply chain and partner connectivity without relying on outdated VANs or legacy tools. Through Youredi’s platform, they deliver managed integrations that support a mix of legacy systems and cloud applications, with built-in data format harmonization and automated validation. That means businesses don’t need to worry about whether partners use XML, JSON, or proprietary formats – the platform handles the translation and consistency behind the scenes.

They also offer support throughout the full integration cycle – developing, deploying, and maintaining connections as part of a managed service. This setup helps companies cut down on in-house IT effort while gaining better visibility and reliability across their ecosystem. Their approach works well for organizations dealing with large-scale trading networks or supply chains, where integration performance directly affects operations and costs.

Key Highlights:

• Fully managed B2B integrations with support from architects
• Hybrid compatibility across cloud and on-premise systems
• Data harmonization across formats like XML, JSON, EDIFACT
• Scalable setup with volume-based processing
• Predictable pricing structure with support tiers

Services:

• iPaaS-based B2B integration
• Modern EDI and data exchange
• Supply chain connectivity
• Integration architecture planning
• Proactive monitoring and support

Contact Information:

• Website: www.coneksion.com
• E-mail: talktous@coneksion.com
• Twitter: x.com/coneksion_SCM
• LinkedIn: www.linkedin.com/company/coneksion
• Address: Revontulenpuisto 2 C, 02100 Espoo, Finland
• Phone: +358 20 735 2084

 

6. Coliance

Coliance provides B2B integration services focused on automating document exchange and streamlining supply chains. Their managed platform connects partners, suppliers, and customers through technologies like EDI, APIs, and web services. These connections help remove manual data handling and reduce errors in transactions like purchase orders, invoices, and shipping notices. Rather than patching together tools, Coliance builds out consistent integration workflows that link core systems across businesses.

They work with clients to unify digital processes while also providing support for system maintenance and updates. The idea is to reduce the day-to-day friction that comes with disconnected systems and instead offer a more hands-off, centralized approach. With a team that understands both the technology stack and the business requirements behind it, Coliance helps clients get more control over how they collaborate with partners – without overcomplicating the process.

Key Highlights:

• Managed platform for end-to-end B2B integration
• Support for both EDI and API-based workflows
• Focus on reducing manual tasks and improving accuracy
• Works across supply chain, finance, and operations
• Flexible support and service delivery

Services:

• B2B integration and file transfer
• Managed EDI and API-based connections
• Application and system unification
• Trading partner onboarding and support
• Workflow design and automation

Contact Information:

• Website: coliance.co
• E-mail: info@coliance.co
• Facebook: www.facebook.com/coliance.co
• Twitter: x.com/colianceco
• LinkedIn: www.linkedin.com/company/Colianceco
• Address: 2nd Floor, 55 Ludgate Hill, London, United Kingdom, EC4M 7JW
• Phone: 01329 888953

 

7. Aonflow

Aonflow offers a unified platform for B2B integration, geared toward connecting business applications and APIs using traditional protocols. Their platform is built around automating processes like order fulfillment, invoicing, and inventory updates. The goal is to reduce repetitive tasks while keeping systems aligned across departments and partner networks. They support both cloud and hybrid deployments, giving companies the flexibility to operate across modern and legacy infrastructure.

One of the defining features of their setup is the low-code interface, which allows non-technical users to build and manage integrations without depending entirely on IT. That reduces development bottlenecks and lets teams respond to process changes more quickly. Aonflow also supports a range of pre-built connectors for ERP, CRM, and eCommerce platforms, which helps cut down on time-to-integration. Their solution focuses less on bells and whistles, and more on delivering usable, configurable tools that work without being fragile.

Key Highlights:

• Low-code platform for faster integration setup
• Hybrid deployment across cloud and on-prem systems
• Pre-built connectors for popular enterprise tools
• Emphasis on automation and real-time visibility
• API-first design with customizable workflows

Services:

• B2B integration for apps and APIs
• Workflow automation and data synchronization
• Low-code configuration tools
• Hybrid integration management
• Secure data exchange and monitoring

Contact Information:

• Website: www.aonflow.com
• E-mail: contact@aonflow.com
• Facebook: www.facebook.com/theaonflow
• Twitter: x.com/AonflowOfficial
• LinkedIn: www.linkedin.com/company/aonflow
• Instagram: www.instagram.com/aonflow.official
• Address: 6303 Owensmouth Ave, 10th floor, Woodland Hills, CA 91367

 

8. TIS Grupa

TIS Grupa focuses on building integrated B2B environments that streamline how businesses communicate and exchange data. Their approach integration is about connecting systems and enabling secure, efficient, and flexible information flow between partners. Their solutions support a wide range of protocols and formats to ensure compatibility across diverse ecosystems, whether it’s legacy platforms or modern APIs. The idea is to remove complexity from daily operations and allow businesses to work together without constantly fixing connection issues.

Their platform covers everything from data mapping and encryption to real-time message tracking and validation. Instead of relying on manual processes or one-size-fits-all tools, they tailor each integration to match how their clients actually work. With support for standards like AS2, SFTP, and HTTP, and built-in tools for translating and compressing large files, they help clients reduce delays, avoid errors, and keep data flowing without interruptions. 

Key Highlights:

• Flexible integration of different protocols, formats, and systems
• Tools for data mapping, validation, encryption, and compression
• Real-time tracking and centralized visibility for message flow
• Adapts to various industries including finance, healthcare, and public services
• Designed for long-term use with ongoing technical support

Services:

• B2B integration platform development
• EDI and API connection setup
• Data format translation and mapping
• Secure file transfer and message validation
• Partner onboarding and integration support

Contact Information:

• Website: tis-grupa.com
• E-mail: info@tis.hr
• Facebook: www.facebook.com/TISGrupa
• LinkedIn: hr.linkedin.com/company/tis-grupa
• Instagram: www.instagram.com/tis_grupa
• Address: Heinzelova 33, 10 000 Zagreb, Hrvatska
• Phone: +385 (0)1 23 55 700

 

9. Cleo

Cleo offers a cloud-based B2B integration platform built around control, automation, and visibility. Their system lets companies manage both API and EDI processes in one place, whether they're automating simple file exchanges or handling more complex multi-partner workflows. Instead of relying on manual scripts or isolated tools, Cleo’s solution is designed to centralize operations and reduce the day-to-day friction of managing integrations across different formats or protocols.

Their users can choose between fully managed services, self-service tools, or a blended model. What makes their approach practical is how much control they hand over – companies can monitor, reprocess, and act on transactions without waiting on external support. The platform includes built-in dashboards, reporting, and the ability to scale to high volumes, which helps businesses stay responsive even when integrations span dozens or hundreds of partners.

Key Highlights:

• Combines API, EDI, and non-EDI integrations into one platform
• Real-time transaction monitoring and dashboard control
• Scalable for high-volume environments
• Supports hybrid self-service and managed models
• Designed for faster onboarding and reduced manual work

Services:

• B2B integration via Cleo Integration Cloud
• Partner onboarding and map reuse
• API/EDI transaction automation
• Issue resolution and data reconciliation tools
• Optional full or partial managed services

Contact Information:

• Website: www.cleo.com
• E-mail: sales@cleo.com
• Facebook: www.facebook.com/CleoSoftware
• Twitter: x.com/cleoneverstops
• LinkedIn: www.linkedin.com/company/cleo-communications
• Address: 4949 Harrison Ave., Suite #200, Rockford, IL 61108
• Phone: +1 815 282 7695

 

10. Quinnox

Quinnox approaches B2B integration as a way to modernize both processes and infrastructure without disrupting business continuity. They help organizations develop strategies tailored to their existing systems, using a mix of cloud platforms, middleware, and industry standards like EDIFACT, X12, and RosettaNet. Their integration solutions focus on making data flow across supply chains, applications, and partner ecosystems more reliable and less manually intensive.

They also offer a managed integration platform hosted in the cloud, which includes partner management tools, monitoring dashboards, and built-in automation for common workflows. Unlike cookie-cutter setups, Quinnox builds each solution to match specific enterprise needs – from API-based integrations to traditional file-based setups. Their platform supports both one-time projects and ongoing maintenance, with options to upgrade or migrate as systems evolve.

Key Highlights:

• Integration built around both business strategy and technical systems
• Wide support for middleware tools and industry data standards
• Cloud-hosted iPaaS with full dashboard visibility
• AI-assisted configuration and low-code customization
• Compliance-ready with secure data handling

Services:

• End-to-end B2B integration strategy and execution
• Cloud-based B2B integration platform (Quinnox B2B Cloud)
• Trading partner management and onboarding
• API, EDI, and metadata-based transformation services
• Ongoing monitoring, upgrades, and support

Contact Information:

• Website: www.quinnox.com
• E-mail: enquiries@quinnox.com
• Facebook: www.facebook.com/QuinnoxInc
• Twitter: x.com/QuinnoxInc
• LinkedIn: www.linkedin.com/company/quinnoxinc
• Address: 1 S Wacker Dr Suite 3150, Chicago, IL 60606, USA
• Phone: +13122196500

 

11. ESSPL

ESSPL works with companies that need smoother data exchange across their supply chains and partner networks. Their focus is on helping organizations replace manual tasks with automated workflows, whether that involves EDI documents, APIs, or other integration methods. They aim to create an environment where systems can pass information without delays, mismatched formats, or extra effort from internal teams. Much of their work revolves around building repeatable processes that keep day-to-day operations running without constant checking.

They also support businesses that deal with many partners, each with different requirements. ESSPL helps with translating document formats, monitoring file movement, and managing the full cycle of order and shipping data. Their team works across various integration tools and standards, giving clients a way to connect older systems with newer platforms. The goal is to make information flow consistently so teams can focus on their core work instead of fixing data issues.

Key Highlights:

• Focus on removing manual data entry and repetitive tasks
• Support for many document formats and EDI standards
• Tools and processes to monitor B2B file status in real time
• Experience working with complex supply chain environments
• Ability to connect different business systems and partner platforms

Services:

• B2B and EDI integration setup and support
• Document translation and mapping
• Automation of order, invoice, and shipping data
• Partner enablement and connection management
• Business activity monitoring and alert

Contact Information:

• Website: www.esspl.com
• E-mail: ess@esspl.com
• Facebook: www.facebook.com/ESSPLtd
• Twitter: x.com/ESSPLcom
• LinkedIn: in.linkedin.com/company/esspl
• Address: 49197 Wixom Tech Dr, Wixom, MI, 48393, USA
• Phone: +91-674-7106000

 

12. Trigyn

Trigyn provides B2B integration services built around helping organizations update older systems and connect better with external partners. Their approach focuses on replacing manual data exchange with automated, secure channels that work across both older on-premise environments and modern cloud setups. They design frameworks that bring together EDI, APIs, and other communication methods into a single structure that teams can monitor and manage more easily.

They also place emphasis on visibility and compliance. Their tools and processes allow users to see transaction status, check partner activity, and maintain secure data handling across the full integration lifecycle. Trigyn supports organizations looking to move away from legacy setups by introducing API-based exchanges, onboarding templates, and monitoring dashboards that help standardize how data moves between partners.

Key Highlights:

• Modernization of legacy EDI environments
• Unified integration approach for APIs, EDI, and cloud systems
• Built-in tools for visibility, monitoring, and auditing
• Focus on secure and compliant data exchange
• Templates and accelerators for faster partner onboarding

Services:

• B2B integration strategy and architecture
• EDI modernization and migration
• API-first B2B integration design
• Partner onboarding tools and self-service portals
• Compliance, monitoring, and lifecycle management

Contact Information:

• Website: www.trigyn.com
• LinkedIn: www.linkedin.com/company/trigyn-technologies
• Address: 100 Metroplex Dr., Suite 301, Edison, NJ 08817
• Phone: 732-777-4600

 

13. Adeptia

Adeptia offers a platform that allows businesses to handle B2B integrations through a no-code, self-service setup. Instead of relying heavily on IT teams to build each new connection, their system is designed so business users can create and adjust integration templates on their own. The platform includes automation tools that clean, map, and process data in the background, reducing the need for manual corrections or repeated work.

Their focus is on simplifying how companies onboard partners and exchange information. Adeptia helps reduce friction by giving users a unified place to build workflows, manage errors, and monitor ongoing activity. With features like AI-driven data mapping and reusable templates, they aim to shorten the time it takes to set up new customer or partner exchanges and keep integrations running smoothly at scale.

Key Highlights:

• No-code platform built for business and IT collaboration
• AI tools for data mapping, cleansing, and enrichment
• Reusable templates for faster integration setup
• Unified view for monitoring and issue handling
• Designed to reduce IT workload and onboarding delays

Services:

• B2B integration through a self-service automation platform
• AI-assisted data mapping and transformation
• Workflow creation and reusable integration templates
• Real-time monitoring and error management
• Support for multi-format data ingestion and automation

Contact Information:

• Website: www.adeptia.com
• LinkedIn: www.linkedin.com/company/adeptia
• Address: 332 S Michigan Ave, Unit LL-A105, Chicago, IL 60604, USA
• Phone: +1 (312) 229-1727

 

14. Actian

Actian offers a fully managed B2B integration service through its Business Xchange platform, aimed at helping companies connect and transact with their partners electronically, regardless of system differences or data formats. Instead of requiring users to manage complex integration processes on their own, Actian handles the full lifecycle – from onboarding and mapping to testing and ongoing support.

Business Xchange allows users to manage procurement and supply chain documents through one connection point, simplifying connections with multiple trading partners. Its cloud-based infrastructure supports document tracking, transaction validation, and KPI dashboards to monitor real-time performance. The platform offers flexibility through web-based forms, file uploads, or direct system integration, while ensuring high reliability and compliance with partner requirements.

Key Highlights:

• Cloud-based, fully managed B2B integration platform
• Handles onboarding, mapping, testing, and ongoing support
• Real-time document tracking and KPI dashboards
• No local software installation required
• Configurable transaction validation and archiving

Services:

• B2B integration-as-a-service
• Electronic procurement and supply chain document exchange
• Trading partner onboarding and management
• Transaction monitoring and analytics dashboards
• Web portal for shared visibility and document control
• Secure attachment handling and document archiving

Contact Information:

• Website: www.actian.com
• Twitter: x.com/ActianCorp
• LinkedIn: www.linkedin.com/company/actian-corporation
• Address: 710 Hesters Crossing Road, Suite 250, Round Rock, TX 78681
• Phone: +1 512 231 6000

 

15. aiDataWorks

aiDataWorks provides B2B consulting and integration services focused on helping companies manage increasingly complex partner ecosystems. Their approach is grounded in both technical and business assessments, with a focus on future-ready architecture that adapts to changing technologies and business growth. The team works across on-premise, cloud, and hybrid environments, offering flexibility in both integration methods and delivery models.

Their services go beyond just connecting systems. They dig into existing partner relationships, system limitations, and protocol mismatches to help organizations shift away from scattered, fragile integrations. Whether the goal is to consolidate communication channels or migrate to new platforms, aiDataWorks helps design and deliver robust integration strategies supported by end-to-end project management.

Key Highlights:

• Deep cross-technology expertise and consulting mindset
• Tailored integration strategies for hybrid and cloud environments
• Flexibility in delivery models: Agile, Waterfall, SAFE, and custom
• Technical and business assessments to align strategy
• Focus on scalability and long-term maintainability

Services:

• Technical assessment of systems and technology stacks
• Business integration planning and architecture design
• Platform migration and data consolidation
• End-to-end data integration across environments
• B2B communication channel streamlining
• Full project management and delivery support across models

Contact Information:

• Website: www.aidata.works

Conclusion

A good way to think about B2B integration is that it’s not really about systems talking to each other, but about people trying to run their operations without constant interruptions. Every company we looked at approaches that challenge from its own angle, yet the common thread is clear: modern business relies on clean, predictable data movement, and the older patchwork methods simply don’t hold up anymore.

As businesses continue to expand their partner networks and rely on more digital processes, the role of B2B integration companies becomes less of an optional upgrade and more of a practical necessity. The value is in reducing noise: fewer manual tasks, fewer mismatches, fewer surprises. When the data moves cleanly, everything else feels a little lighter. And while the specifics differ from one provider to another, the goal is essentially the same – making collaboration less of a hurdle and more of a natural part of how the business operates.